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Bosphore FMF Mutation Analysis Kit v2

Bosphore® FMF Mutation Analysis Kit v2, is a Real-Time PCR-based in vitro diagnostic medical device, IVD CE marked according to 98/79/EC Directive. Bosphore® FMF Mutation Analysis Kit v2 detects the mutations M694I, M694V, M680I/GA, M680I/GC, V726A, R761H, A744S, K695R on Exon 10, P369S on Exon 3, F479L on Exon 5 and E148Q, R202Q mutations on Exon 2 of MEFV gene in human blood samples. Wild type alleles are amplified and fluorescence detection is accomplished using the HEX filter. Mutant alleles are amplified and fluorescence detection is accomplished using the FAM filter.

 

  • In the 1st well: M694I mutation,
  • 2nd well: M694V mutation,
  • 3rd well: Guanine-Adenine alteration resulted M680I mutation,
  • 4th well: Guanine-Cytosine alteration resulted M680I mutation,
  • 5th well: V726A mutation,
  • 6th well: R761H mutation
  • 7th well: E148Q mutation,
  • 8th well: A744S mutation,
  • 9th well:  K695R mutation,
  • 10th well:  P369S mutation,
  • 11th well: F479L mutation,
  • 12th well: R202Q mutations are detected. 

 

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AUTOMATED EXTRACTION SYSTEMS

 

 

MANUAL EXTRACTION SYSTEMS

 

 

REAL-TIME PCR DEVICES